A strict keto diet requires close management by a health professional. It should be mentioned here that the duration of the KD may play a crucial role in its efficacy. This is perhaps related to the fact that full ketogenic metabolic adjustment (keto-adaptation) requires about 7 days . Dietary interventions with a KD lasting less than 2 weeks seem to be insufficient to reveal the real effects of ketosis. It is thus crucial to verify that the state of ketosis has been achieved via an evaluation of the level of KB in the urine and/or blood.